Two things occur to me:

1). People in online popular culture no longer talk about “body positivity” now that GLP-1 drugs are readily available and have proven to be somewhat effective. However, I remember the coming and going of Olestra, so I’m waiting for the other shoe to drop.

2). There is never going to be a chemical solution to the pile of psychological, emotional, and spiritual factors that cause the differing disorders, pathologies, habits, tendencies, and tics that humans experience as a result of living in a fallen world.

Of course, I am trade-off positive rather than solution positive, because the abyss of human nature is as deep and dark as the abyss Nietzsche rhapsodized about in his various mad warnings.